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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK3
All Species:
64.85
Human Site:
S46
Identified Species:
89.17
UniProt:
Q00526
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00526
NP_001249.1
305
35046
S46
L
E
M
E
G
V
P
S
T
A
I
R
E
I
S
Chimpanzee
Pan troglodytes
XP_523720
325
36841
S66
L
E
M
E
G
V
P
S
T
A
I
R
E
I
S
Rhesus Macaque
Macaca mulatta
XP_001102596
305
34903
S46
L
E
M
E
G
V
P
S
T
A
I
R
E
I
S
Dog
Lupus familis
XP_540442
303
34173
S46
L
E
T
E
G
V
P
S
T
A
I
R
E
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80YP0
303
33870
S46
L
E
A
E
G
V
P
S
T
A
V
R
E
I
S
Rat
Rattus norvegicus
Q63699
298
33869
S46
T
E
T
E
G
V
P
S
T
A
I
R
E
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
S46
S
E
E
E
G
V
P
S
T
A
I
R
E
I
S
Frog
Xenopus laevis
P23437
297
33852
S46
T
E
T
E
G
V
P
S
T
A
I
R
E
I
S
Zebra Danio
Brachydanio rerio
NP_998571
298
34001
S46
T
E
T
E
G
V
P
S
T
A
I
R
E
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
S46
S
D
D
E
G
V
P
S
T
A
I
R
E
I
S
Honey Bee
Apis mellifera
XP_393450
299
34033
S46
T
E
S
E
G
V
P
S
T
A
I
R
E
I
S
Nematode Worm
Caenorhab. elegans
P34556
332
38277
S64
S
E
D
E
G
V
P
S
T
A
V
R
E
I
S
Sea Urchin
Strong. purpuratus
XP_790847
299
34142
S46
T
E
S
E
G
V
P
S
T
A
I
R
E
I
A
Poplar Tree
Populus trichocarpa
XP_002306004
294
33768
S46
Q
E
D
E
G
V
P
S
T
A
I
R
E
I
S
Maize
Zea mays
P23111
294
33816
S46
Q
E
D
E
G
V
P
S
T
A
I
R
E
I
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
S46
Q
E
D
E
G
V
P
S
T
A
I
R
E
I
S
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
S53
S
E
D
E
G
V
P
S
T
A
I
R
E
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
96.7
88.5
N.A.
82.6
74.7
N.A.
N.A.
63.6
73.7
73.7
N.A.
62.9
67.2
58.1
69.5
Protein Similarity:
100
93.5
98.3
92.7
N.A.
91.8
84.5
N.A.
N.A.
78
84.5
83.2
N.A.
76.7
80.6
69.5
82.6
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
86.6
86.6
86.6
N.A.
80
86.6
80
80
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
N.A.
86.6
86.6
86.6
N.A.
86.6
86.6
86.6
86.6
Percent
Protein Identity:
65.2
64.2
N.A.
65.5
62.3
N.A.
Protein Similarity:
81.6
80.9
N.A.
81.3
77.7
N.A.
P-Site Identity:
86.6
86.6
N.A.
86.6
86.6
N.A.
P-Site Similarity:
86.6
86.6
N.A.
86.6
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
0
0
0
0
0
100
0
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
36
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
95
6
100
0
0
0
0
0
0
0
0
100
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
89
0
0
100
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
18
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% P
% Gln:
18
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% R
% Ser:
24
0
12
0
0
0
0
100
0
0
0
0
0
0
95
% S
% Thr:
30
0
24
0
0
0
0
0
100
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
100
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _